Experience
Professional Journey
Tracing My Path Through Industry and Academia: A Record of Dedicated Research and Development.
Experience Overview
Harvard Medical School
Research Fellow in Neurology
Jul 2024 - Present
Cambridge, Massachusetts, United States · On-site
Department of Pharmacological and Pharmaceutical Sciences
Graduate Researcher Organic Chemist/Medicinal Chemist.
Full-time Sep 2018 - Dec 2023 · 5 yrs 4 mos | Greg Cuny
Houston, Texas, United States
Planning, Research & Analytics
Developed synthetic methodologies, resulting in a 34% improvement in overall production efficiency.
Optimized synthetic routes for key product lines, increasing final product yields from 23% to 85%.
Utilized advanced molecular modelling techniques to design 50 novel molecules, resulting in a 30% increase in potency of drug candidate.
Drug Design & Development
Designed and optimized 20+ RIPK2 small molecule inhibitors, resulting in a 60% reduction in Multiple Sclerosis symptoms.
Developed a streamlined process for synthesizing PROTACs for MLKL, reducing production time by 40% and showcasing potential savings in manufacturing costs.
Collaborated with UH computational chemistry and Tufts biology teams to develop a novel research methodology that led to the successful crystallization of the first human MLKL bound to its activator, advancing understanding of necroptosis pathway mechanisms.
Technical Reports & Collaboration
Collaborated with other researchers to conduct comprehensive preclinical studies on bioactive molecules, identifying 5 promising compounds, and selecting a lead candidate for advanced research and therapeutic development.
Drafted and submitted patent applications for groundbreaking small molecule activators of MLKL pseudokinase, contributing to the successful filing of the patents within 2 months.
Research Assistant
Developed innovative synthetic routes for the total synthesis of Cytoblastin, significantly reducing reaction time and increasing overall yield by 20%.
Analyzed and interpreted experimental data, leading to the identification of key trends and insights that informed future research directions.
University of Massachusetts Boston
Undergraduate Researcher
Mar 2016 - May 2018 · 2 yrs 3 mos | Umb.edu
Greater Boston Area, United States
Working on a research project investigating the role of Liquid Chromatography and Mass Spectrometry (LCMS) in Proteomics.
Evaluating the accuracy, precision and coverage of MS3 method of quantifying proteins.
Developed an enhanced method of Mass Spectrometry, resulting in 30% more reliable proteomics experiments.
Working on a research project investigating the role of Liquid Chromatography and Mass Spectrometry (LCMS) in Proteomics.
Evaluating the accuracy, precision and coverage of MS3 method of quantifying proteins.
Developed an enhanced method of Mass Spectrometry, resulting in 30% more reliable proteomics experiments.
Chemistry Tutor
Part-time Aug 2016 - Dec 2016 · 5 mos
Greater Boston Area, United States
Developed action plans based on students’ and educators’ academic goals to teach analytical chemistry to other students.
Harvard Medical School
Research Assistant
Jun 2017 - Dec 2017 · 7 mos | Shafiee Lab
Cambridge, Massachusetts, United States · On-site
Designing and developing engineering systems with clinical applications.
Learning about the basics of diagnostic device development and optimization.
Developing diagnostics using micro fluidics and electrical and optical modalities for sensing.
Fabricating paper based micro fluidic chip for capturing and detecting cells.
Developed point-of-care diagnostic assays using microfluidics, enhancing disease detection accuracy.
Collaborated in engineering of a novel platform for HIV-1 detection using mobile health and bioengineered catalytic motors with 99.1% specificity and 94.6% sensitivity.
Tufts University School of Medicine
Research Assistant
Jan 2017 - Jun 2017 · 6 mos | Yelick Lab
Boston, Massachusetts, United States · On-site
nvestigating the effect of injury in Zebrafish with overactive BMP signaling which is important in Fibrodysplasia Ossificans Progressiva disease.
Performed set-up and preparation procedures, developed and implemented quality control procedures for research methodology.
Assisted with preparation for and conducting of experiments.
Prepared and maintained laboratory equipment before and after work.
ENRICHMENT PROGRAM – PATHWAY TO PH.D.
Jan 2017 - Feb 2017 · 2 mos On-site
Boston, Massachusetts, United States · On-site
Explored and practiced different laboratory techniques and methods.
Collaborated with School of Biomedical Sciences to conduct hands-on research in microbiology, immunology, neuroscience, and cancer biology.
U.S. Department of Veterans Affairs
VA Caregiver
Full-time 2016 - 2023 · 7 yrs | VA
Houston, Texas, United States
Maintain records of patient care, condition, progress, or problem to report and discuss observation with doctors or case managers.
Check patients’ pulse, temperature, and respiration.
Administer prescribed oral medication, under the written direction of a physician or as directed by home care nurse or aide, and ensure patients take their medicine.
Maintain accurate, detailed report and records.
Modify patient treatments plan as indicated by patients’ responses and condition.
Monitor all aspects of patient care, including diet and physical activity.
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Bridging the gap in the biomedical sciences
Long-running program introduces undergraduates from backgrounds underrepresented in medicine and science to biomedical research, mentors in the field
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Develops Smartphone Fertility Tests
Harvard’s Dr. Hadi Shafiee unites developments in fertility medicine with new technology. His work aims to make previously complicated tests – such as ovulation tests and male fertility tests – a simple, affordable process that can be done at home.
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Undergrads interested in medicine and science
UMass Boston students pursuing careers in medicine or biomedical sciences take part in a Tufts curriculum targeting disparities in the clinical and biomedical workforce
